Sunday, November 30, 2025

Large Information For Your Mind

However first . . .

Because the deal to reopen the federal government lasts solely till the tip of January, don’t we get to do that once more in a number of weeks if the Republicans proceed to refuse to fulfill their constituents’ healthcare wants?

Within the meantime, we’ve reopened the federal government, staving off large hardship and financial loss . . .

. . . and proven that we’re those who need to feed poor children and seniors and veterans on meals stamps . . . we’re those who need folks to have inexpensive well being care . . . they’re those who battle this stuff, preferring tax cuts for billionaires and $40 billion for Argentina.

(Not that I’ve something in opposition to Argentina.)

In the event that they don’t come to their sense and relent, we simply resume the battle in January, once they’ll once more want our votes to maintain the federal government open, having proven that we actually did give them each alternative to do the appropriate factor.

No?

Apologies upfront if I’m being dense.  I used to be in laptop hell a lot of the day.



WITH LIBERTY AND JUSTICE FOR SOME

If you happen to commit crimes for Trump or can bribe him adequately, you get a pardon.  If you happen to oppose him, you get indicted.

Decide Mark L. Wolf lays it out so superbly:

Why I Am Leaving the Federal Bench

It’s to cry.


Felon Freed by Trump Is Sentenced Once more, This Time to 27 Months

And (as you’ll see when you’ve got time to learn it) he’s hardly the one one.


The lack of an expert, apolitical Justice Division strikes me as 10,000 instances extra essential than (say) who makes use of what lavatory (does the federal authorities actually need to become involved?) or Hunter Biden’s laptop computer (if there have been one thing of actual significance on it, wouldn’t the Trump regime have launched it by now?).



HURRICANE SEASON

Out of your superb fellow reader Bryan Norcross: no extra this yr; A.I. is now the perfect predictor.



And now . . .

HUGE NEWS FOR YOUR BRAIN

Out of your superb fellow reader Jeff Zimman, Co-founder of BrainHQ mother or father Posit Science:


In case you missed it, I needed to share large information from an NIH-funded research that has gotten an outpouring of press throughout the globe due to its enormous implications for getting older and dementia.

A neuroimaging crew at McGill discovered 10 weeks of every day BrainHQ coaching drove important and substantial rejuvenation within the mind’s cholinergic system.

It’s the system that produces acetylcholine (the “listen” chemical) on the exact second it’s wanted.

We’ve recognized for many years that this method turns into more and more sluggish (downregulates) with regular getting older and plummets with pre-dementia and Alzheimer’s.

In truth, probably the most prescribed class of medicine for Alzheimer’s – cholinesterase inhibitors comparable to Aricept® – artificially flood the mind with acetylcholine to offer some transient reduction, however don’t repair the underlying sluggishness in its manufacturing.

BrainHQ simply grew to become the first intervention of any variety proven to upregulate acetylcholine manufacturing.

The upregulation from 10 weeks of BrainHQ coaching at half-hour per day was about equal to the quantity a median older grownup downregulates over a decade. And the acquire persevered 3 months after the coaching ended.

The management group did attentionally demanding on-line video games (like solitaire and sweet crush) for an equal period of time and confirmed no enchancment.

As famous by the researchers, WHAT you do issues — simply staying mentally lively will not be sufficient.

The research supplies a bio-chemical rationalization of how BrainHQ rewires the mind and why BrainHQ, uniquely, has gotten the outcomes seen throughout tons of of research. The implications for getting older, pre-dementia and Alzheimer’s are compelling, and a brand new NIH grant has been awarded to do the same research in MCI (pre-dementia). Many different situations are related to deficiencies in mind chemical compounds which BrainHQ can be designed to upregulate, suggesting a novel pathway for remedy.

I imagine historians will view this research as pivotal within the improvement of interventions to handle quite a few well being situations and likewise to assist us all with improved peak efficiency (e.g., Tom Brady).

This text was initially revealed on November eleventh, 2025 on andrewtobias.com, syndicated with permission.

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